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[淋巴细胞白血病患儿红细胞中的葡萄糖磷酸脱氢酶活性及还原型谷胱甘肽水平]

[Glucosephosphate dehydrogenase activity and reduced glutathione level in the erythrocytes of children with lymphoblastic leukemia].

作者信息

Warchoł T, Radwańska U, Karoń H

出版信息

Acta Haematol Pol. 1981 Apr-Jun;12(2):85-9.

PMID:6946662
Abstract

The activity of glucose-6-phosphate dehydrogenase and the level of reduced glutathione were determined in the erythrocytes of children with acute lymphoblastic leukaemia treated by intensive combined chemotherapy (according to the authors from Memphis). The determinations were done before, during and after completion of treatment lasting about 3 years. A significant rise was observed in the activity of this enzyme and in the level of reduced glutathione in the groups of treated children and their fall to normal values after completion of treatment.

摘要

对接受强化联合化疗(据孟菲斯的作者所述)的急性淋巴细胞白血病患儿的红细胞,测定了葡萄糖 - 6 - 磷酸脱氢酶活性和还原型谷胱甘肽水平。测定在持续约3年的治疗前、治疗期间和治疗完成后进行。观察到接受治疗的患儿组中该酶的活性和还原型谷胱甘肽水平显著升高,且在治疗完成后降至正常水平。

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