Goudemand M, Goudemand J, Goudemand-Joubert C, Parquet P J
Acta Psychiatr Belg. 1981 Jan-Feb;81(1):57-71.
We first consider current arguments in favor of a genetic etiology of childhood psychoses. These psychoses have to be separated in early psychoses (before age 5) and late onset ones (between 5 years and adolescence). These late onset psychoses appear to be genetically determined and related to schizophrenia, while early psychoses may be in part genetically related and subject to environmental factors. We also report a study on HLA in early onset psychoses in the North of France, which could not show any association between HLA system and the psychoses.
我们首先考虑目前支持儿童期精神病存在遗传病因的观点。这些精神病必须分为早发性精神病(5岁之前)和晚发性精神病(5岁至青春期之间)。这些晚发性精神病似乎由基因决定,且与精神分裂症相关,而早发性精神病可能部分与基因有关,且受环境因素影响。我们还报告了一项针对法国北部早发性精神病患者的人类白细胞抗原(HLA)研究,该研究未发现HLA系统与这些精神病之间存在任何关联。