由DNA聚合酶γ从病毒DNA合成细小病毒H-1复制型。
Synthesis of parvovirus H-1 replicative form from viral DNA by DNA polymerase gamma.
作者信息
Kollek R, Goulian M
出版信息
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6206-10. doi: 10.1073/pnas.78.10.6206.
Abstract
The initial event in the replication cycle of parvovirus H-1 is conversion of the single-stranded linear viral DNA to the double-stranded linear replicative form. We describe here detection of an activity in uninfected cell extracts that carries out this reaction. The activity was purified and identified as DNA polymerase gamma.
摘要
细小病毒H-1复制周期的起始事件是单链线性病毒DNA转化为双链线性复制形式。我们在此描述了在未感染细胞提取物中检测到的进行此反应的一种活性。该活性被纯化并鉴定为DNA聚合酶γ。
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