Carlon C, Teba L, Maloney B, Parker S
Intensive Care Med. 1981;7(6):313-4. doi: 10.1007/BF01709730.
A 25-year-old patient, with multiple pulmonary metastases from osteogenic sarcoma who two years ago developed respiratory failure with unilateral left lung involvement and was successfully treated with independent lung ventilation, was readmitted to an ICU with recurrent unilateral lung disease. Conventional therapy failed to reverse the respiratory failure; independent ventilation temporarily improved the patient's oxygenation. At autopsy, different involvement of the two lungs by the tumor was evident so that blood flow of the right lung and lymphatic flow of the left lung were impaired. When respiratory failure unresponsive to conventional therapy develops, anatomical abnormalities should be considered.
一名25岁的骨肉瘤肺转移患者，两年前因左侧单肺受累出现呼吸衰竭，并通过独立肺通气成功治疗，现因复发性单侧肺部疾病再次入住重症监护病房。常规治疗未能逆转呼吸衰竭；独立通气暂时改善了患者的氧合。尸检时，明显可见肿瘤对两肺的累及情况不同，导致右肺血流和左肺淋巴引流受损。当出现对常规治疗无反应的呼吸衰竭时，应考虑解剖学异常。
