Lundgren B, Helleberg A
J Natl Cancer Inst. 1982 Mar;68(3):351-5.
A population, originally 6,845 women, 40 years of age and over, was screened for breast cancer by single oblique-view mammography in 1974, 1977, and 1980. Of the 5,789 women remaining in their parish in 1980, 94% had attended the screening at least once. Of 111 breast cancers diagnosed in the 6.25-year study period, 78% were detected at screening, 15% as interval cancers, and 7% among nonresponders. Sixty-three percent of the women had tumors in clinical stage I, and 59% had tumors less than or equal to 10 mm. The predictive value for biopsy recommendations by mammography was 79%. This method was considered very suitable for screening. In the older age groups there was probably some overdiagnosis of cancers that would never have become symptomatic.
1974年、1977年和1980年,对最初的6845名40岁及以上女性进行了单斜位乳房X线摄影筛查乳腺癌。1980年留在其教区的5789名女性中,94%至少参加过一次筛查。在6.25年的研究期间诊断出的111例乳腺癌中,78%在筛查时被发现,15%为间期癌,7%在未参与者中被发现。63%的女性肿瘤处于临床I期,59%的女性肿瘤小于或等于10毫米。乳房X线摄影对活检建议的预测价值为79%。该方法被认为非常适合筛查。在年龄较大的人群中,可能存在一些对永远不会出现症状的癌症的过度诊断。