Marder M Z, Deesen K C
J Am Dent Assoc. 1982 Jul;105(1):55-60. doi: 10.14219/jada.archive.1982.0036.
We have presented a case of malignant transformation of oral lichen planus along with a review of the literature and a brief description of the disease. We have attempted to indicate that within defined terms, oral lichen planus should be considered a pre-malignant lesion in which incidence of transformation approaches that of clinical oral leukoplakia, yet is clearly distinctive from that disease with regard to age and sex distribution. The erosive form of oral lichen planus most often precedes carcinomatous change. A protocol is described for documentation and periodic follow-up procedures for such patients to possibly intercept a developing malignancy.
我们报告了一例口腔扁平苔藓恶变的病例，并对相关文献进行了综述，对该疾病作了简要描述。我们试图指出，在明确的定义范围内，口腔扁平苔藓应被视为一种癌前病变，其恶变发生率接近临床口腔白斑，但在年龄和性别分布方面与该疾病明显不同。口腔扁平苔藓的糜烂型最常先于癌变。本文描述了针对此类患者的记录和定期随访程序方案，以便可能及时发现正在发展的恶性肿瘤。
