小分子-脂质双层混合物的扫描量热研究。
A scanning calorimetric study of small molecule-lipid bilayer mixtures.
作者信息
Sturtevant J M
出版信息
Proc Natl Acad Sci U S A. 1982 Jul;79(13):3963-7. doi: 10.1073/pnas.79.13.3963.
Abstract
The influence of small molecules on the main phase transition of dimyristoyl phosphatidylcholine was observed by high-sensitivity differential scanning calorimetry. The variation with temperature of the excess heat capacity is markedly affected by solid solution formation, which appears to be of frequent occurrence in solutions in lipid bilayers. The experimental results are in some cases in reasonable agreement with ideal solution theory.
摘要
通过高灵敏度差示扫描量热法观察了小分子对二肉豆蔻酰磷脂酰胆碱主相变的影响。过量热容随温度的变化受到固溶体形成的显著影响，固溶体形成似乎在脂质双层溶液中经常发生。在某些情况下，实验结果与理想溶液理论合理吻合。
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