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本文引用的文献

1
Thermodynamics of partitioning and efflux of phenothiazines from liposomes.吩噻嗪类药物从脂质体的分配与外排的热力学
J Membr Biol. 1981 Feb 28;58(3):181-9. doi: 10.1007/BF01870904.
2
The solubility of amphipathic molecules in biological membranes and lipid bilayers and its implications for membrane structure.两亲性分子在生物膜和脂质双分子层中的溶解性及其对膜结构的影响。
Biochemistry. 1981 Feb 17;20(4):808-18. doi: 10.1021/bi00507a024.
3
Membrane:buffer partition coefficient for ethanol in dimyristoylphosphatidylcholine.膜:二肉豆蔻酰磷脂酰胆碱中乙醇的膜-缓冲液分配系数
Alcohol Clin Exp Res. 1981 Spring;5(2):259-63. doi: 10.1111/j.1530-0277.1981.tb04899.x.
4
The membrane concentrations of alcohol anesthetics.酒精麻醉剂的膜浓度。
Biochim Biophys Acta. 1971 Feb 2;225(2):171-84. doi: 10.1016/0005-2736(71)90210-0.
5
Nonsolvent water in liposomes.脂质体中的非溶剂水。
J Membr Biol. 1974;17(1):87-100. doi: 10.1007/BF01870174.
6
The effect of anaesthetic-like molecules on the phase transition in smectic mesophases of dipalmitoyllecithin. I. The normal alcohol up to C equals 9 and three inhalation anaesthetics.麻醉样分子对二棕榈酰卵磷脂近晶相液晶相转变的影响。I. 碳原子数小于等于9的正构醇及三种吸入性麻醉剂。
Biochim Biophys Acta. 1974 Jul 12;356(1):117-24. doi: 10.1016/0005-2736(74)90299-5.
7
A method for measuring nonelectrolyte partition coefficients between liposomes and water.一种测量脂质体与水之间非电解质分配系数的方法。
J Membr Biol. 1974;17(1):69-86. doi: 10.1007/BF01870173.
8
Interpretation of nonelectrolyte partition coefficients between dimyristoyl lecithin and water.二肉豆蔻酰卵磷脂与水之间非电解质分配系数的解释。
J Membr Biol. 1974;17(2):121-54. doi: 10.1007/BF01870176.
9
Thermodynamic constants for nonelectrolyte partition between dimyristoyl lecithin and water.二肉豆蔻酰卵磷脂与水之间非电解质分配的热力学常数。
J Membr Biol. 1974;17(2):101-20. doi: 10.1007/BF01870175.
10
Shape of the hydrophobic barrier of phospholipid bilayers (evidence for water penetration in biological membranes).磷脂双分子层疏水屏障的形状(生物膜中水渗透的证据)
J Membr Biol. 1974;15(2):159-92. doi: 10.1007/BF01870086.

小分子-脂质双层混合物的扫描量热研究。

A scanning calorimetric study of small molecule-lipid bilayer mixtures.

作者信息

Sturtevant J M

出版信息

Proc Natl Acad Sci U S A. 1982 Jul;79(13):3963-7. doi: 10.1073/pnas.79.13.3963.

DOI:10.1073/pnas.79.13.3963
PMID:6955783
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC346556/
Abstract

The influence of small molecules on the main phase transition of dimyristoyl phosphatidylcholine was observed by high-sensitivity differential scanning calorimetry. The variation with temperature of the excess heat capacity is markedly affected by solid solution formation, which appears to be of frequent occurrence in solutions in lipid bilayers. The experimental results are in some cases in reasonable agreement with ideal solution theory.

摘要

通过高灵敏度差示扫描量热法观察了小分子对二肉豆蔻酰磷脂酰胆碱主相变的影响。过量热容随温度的变化受到固溶体形成的显著影响,固溶体形成似乎在脂质双层溶液中经常发生。在某些情况下,实验结果与理想溶液理论合理吻合。