水溶性溶质对磷脂相变的影响。
The effects of water-soluble solutes on the phase transitions of phospholipids.
作者信息
Sturtevant J M
出版信息
Proc Natl Acad Sci U S A. 1984 Mar;81(5):1398-400. doi: 10.1073/pnas.81.5.1398.
Abstract
A previous treatment [Sturtevant, J.M. (1982) Proc. Natl. Acad. Sci. USA 79, 3963-3967], based on ideal solution theory, of the influence of small molecules on the main phase transitions of phospholipid bilayers is extended to include the effect of water solubility of the added solute. This effect is manifested primarily in a sharpening of the phase transition, resulting from a buffering by the aqueous phase of the concentration of the solute in the lipid phases.
摘要
先前基于理想溶液理论对小分子对磷脂双层主相变影响的一种处理方法[斯特蒂文特，J.M.（1982年）《美国国家科学院院刊》79卷，3963 - 3967页]得到了扩展，以纳入添加溶质的水溶性影响。这种影响主要表现为相变的锐化，这是由于水相对脂质相中溶质浓度的缓冲作用所致。
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