大鼠中前列腺素E2、阿托品、哌仑西平和迷走神经切断术的细胞保护作用
Cytoprotection by PGE2, atropine, pirenzepine and vagotomy in rats.
作者信息
Rovati V, Foschi D, Ferrante F, Del Soldato P, Daniotti S, Varin L
出版信息
Scand J Gastroenterol Suppl. 1982;72:261-4.
PMID:6957994
Abstract
Gastric cytoprotective effects of vagotomy, PGE2 and antimuscarinic compounds (pirenzepine, atropine) were studied in the rat. Both pharmacological and surgical treatment prevented the gastric damage induced by intragastric administration of acetylsalicylic acid plus hydrochloric acid. The mechanisms of action are discussed.
摘要
在大鼠中研究了迷走神经切断术、前列腺素E2（PGE2）和抗毒蕈碱化合物（哌仑西平、阿托品）的胃细胞保护作用。药理学和手术治疗均能预防胃内给予乙酰水杨酸加盐酸所诱导的胃损伤。对作用机制进行了讨论。
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