Sato T, Takeuchi A
Vet Pathol Suppl. 1982 Sep;7:17-25.
Light and electron microscopy showed gastric spirilla in the gastric mucosa of 45 clinically normal rhesus monkeys (Macaca mulatta). In paraffin sections, gastric spirilla were best shown by silver impregnation stains. When stained by hematoxylin and eosin (HE), gastric spirilla may be mistaken for strands of mucus. In thick sections of epon-embedded tissue, gastric spirilla looked like "corkscrews" with up to 12 coils. They were 8 microns long and 0.7 microns wide, and had characteristic bipolar flagella. They were concentrated in the gastric glands at the isthmus, were less common at the neck and base, and were absent in the gastric lumen. Gastric spirilla were associated closely with parietal cells and could penetrate their cytoplasm. Gastric spirilla elicit neither changes of host cytocomponents nor an inflammatory response in the gastric mucosa.
光镜和电镜检查显示，45只临床正常的恒河猴（猕猴）胃黏膜中有胃螺旋菌。在石蜡切片中，胃螺旋菌用银浸染染色显示效果最佳。用苏木精和伊红（HE）染色时，胃螺旋菌可能会被误认为是黏液丝。在环氧树脂包埋组织的厚切片中，胃螺旋菌看起来像有多达12个螺旋的“开塞钻”。它们长8微米，宽0.7微米，有特征性的双极鞭毛。它们集中在峡部的胃腺中，在颈部和底部较少见，胃腔中则没有。胃螺旋菌与壁细胞密切相关，可穿透其细胞质。胃螺旋菌既不引起宿主细胞成分的变化，也不引起胃黏膜的炎症反应。
