Aoyagi K, Mishima Y, Murakami S, Ito K
Bull Tokyo Med Dent Univ. 1982 Dec;29(4):153-9.
To study the gastrointestinal hormones in hyperthyroidism and the interrelations with the thyroid hormones, the preprandial serum gastrin and motilin were measured by radioimmunoassay in 104 patients before and after the treatments. The following results were obtained: 1) Serum gastrin concentration in hyperthyroidism was significantly higher than that of the control, and when the patients reached euthyroidism or hypothyroidism after the treatments, the gastrin concentrations in the serum decreased to the normal level. There was a positive correlation between the thyroid hormones and the serum gastrin. 2) Serum motilin concentration in hyperthyroidism was slightly lower than that of the control. As the patients reached the euthyroid or hypothyroid state after the treatments, an increasing tendency of motilin was observed, though the change was not significant. There was a slightly negative correlation in gastrin versus motilin and also in T4 versus motilin.
为研究甲状腺功能亢进症患者的胃肠激素及其与甲状腺激素的相互关系，采用放射免疫分析法对104例患者治疗前后的空腹血清胃泌素和胃动素进行了检测。结果如下：1）甲状腺功能亢进症患者血清胃泌素浓度显著高于对照组，治疗后患者达到甲状腺功能正常或减退状态时，血清胃泌素浓度降至正常水平。甲状腺激素与血清胃泌素呈正相关。2）甲状腺功能亢进症患者血清胃动素浓度略低于对照组。治疗后患者达到甲状腺功能正常或减退状态时，胃动素呈上升趋势，尽管变化不显著。胃泌素与胃动素之间以及T4与胃动素之间存在轻度负相关。
