Phillips C, Shapiro P A, Luschei E S
Am J Orthod. 1982 Apr;81(4):292-8. doi: 10.1016/0002-9416(82)90214-7.
In two adolescent male Macaca mulatta monkeys, small unilateral electrolytic lesions were produced in the motor nucleus of the trigeminal nerve. The side contralateral to the muscle paralysis served as the control side. The animals were killed 130 and 300 days postoperatively. One animal (animal A) was prepared as a dry skull preparation. Alterations in craniofacial form were noted clinically in both animals and included paralysis and atrophy of the muscles of mastication on the lesion side and mandibular asymmetry. In animal A (300 days postoperative survival), alterations in form included dental and mandibular asymmetry, the appearance of an anterior open-bite on the affected side, and a decrease in the size of the intratemporal fossa on the affected side. Remodeling changes were evident in the condylar process, the zygomatic arch, the orbit, and the zygomaticotemporal and zygomaticofrontal sutures on the lesion side but were not apparent on the contralateral side.
在两只青春期雄性恒河猴身上，在三叉神经运动核制造了小的单侧电解损伤。肌肉麻痹对侧作为对照侧。动物在术后130天和300天处死。一只动物（动物A）制成干颅骨标本。两只动物临床上均观察到颅面形态改变，包括损伤侧咀嚼肌麻痹和萎缩以及下颌不对称。在动物A（术后存活300天），形态改变包括牙齿和下颌不对称、患侧出现前牙开合以及患侧颞下窝变小。损伤侧的髁突、颧弓、眼眶以及颧颞缝和颧额缝有明显的重塑变化，而对侧不明显。
