超急性变应性脑脊髓炎：单一决定因素。
Hyperacute allergic encephalomyelitis: a single determinant.
作者信息
Westall F C
出版信息
Immunol Commun. 1977;6(3):227-37. doi: 10.3109/08820137709050794.
HEAE cannot be induced in either guinea pigs using 10(10) or 20x10(10) organisms of B. pertussis or in rabbits using 4x10(10) organisms of B. pertussis and basic protein from the following species: guinea pig, Lewis rat, human, bovine, porcine, monkey and rabbit. The only encephalitogenic region for Lewis rats which also produces HEAE in Lewis rats is not encephalitogenic in either rabbits or guinea pigs. Therefore it seems highly probably that there is only one HEAE determinant for all species which are able to express HEAE.
使用10(10)或20×10(10)个百日咳博德特氏菌在豚鼠中不能诱发过敏性脑脊髓炎，使用4×10(10)个百日咳博德特氏菌和来自以下物种的碱性蛋白在兔子中也不能诱发：豚鼠、刘易斯大鼠、人、牛、猪、猴和兔子。对刘易斯大鼠而言，唯一能在其体内产生过敏性脑脊髓炎的致脑炎区域，在兔子或豚鼠中却不具有致脑炎作用。因此，对于所有能够表现出过敏性脑脊髓炎的物种来说，似乎极有可能只有一种过敏性脑脊髓炎决定簇。
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