Lindeberg H, Halaburt H, Larsen P O
J Maxillofac Surg. 1982 Nov;10(4):246-9. doi: 10.1016/s0301-0503(82)80048-9.
Eight living patients with the nevoid basal cell carcinoma syndrome (NBS) underwent a clinical and radiological examination, and data on a deceased patient was included. Cerebral CT-scannings were performed on eight patients, and calcification in the falx and tentorium cerebelli was found in all patients but one. Congenital hydrocephalus or agenesis of the corpus callosum could not be demonstrated. Laboratory results, including serum levels of alpha 1-antitrypsin and alpha 2-macroglobulin, haptoglobin, inorganic phosphorus, alkaline phosphatase and calcium, were normal in all patients but two. It is postulated that elevated serum alkaline phosphatase in patients with NBS is correlated to the presence of growing odontogenic keratocysts.
八名患有痣样基底细胞癌综合征（NBS）的在世患者接受了临床和放射学检查，并纳入了一名已故患者的数据。对八名患者进行了脑部CT扫描，除一名患者外，其他所有患者均在大脑镰和小脑幕发现钙化。未发现先天性脑积水或胼胝体发育不全。除两名患者外，所有患者的实验室检查结果均正常，包括血清α1-抗胰蛋白酶、α2-巨球蛋白、触珠蛋白、无机磷、碱性磷酸酶和钙水平。推测NBS患者血清碱性磷酸酶升高与正在生长的牙源性角化囊肿的存在有关。
