Kosakai N, Mori M, Shitara M, Kudo M, Morimoto M
Jpn J Antibiot. 1982 Aug;35(8):1934-44.
The antibacterial activities of Staph. aureus isolated in 1980 and 1981 at all districts in Japan to ABPC, CEZ, CMZ and GM were tested. Numbers of test strains were 587 strains in 1980 and 700 strains in 1981, respectively. The frequencies of ABPC and CEZ resistant strains of Staph. aureus (MIC: greater than or equal to 25 micrograms/ml) were clearly increased in annual variation. The percentage of CEZ resistant strains in 1981 tested by 10(8) CFU/ml inoculum size was 12.3%, but the same of CMZ was only 0.6%.
对1980年和1981年日本各地区分离出的金黄色葡萄球菌针对氨苄青霉素（ABPC）、头孢唑啉（CEZ）、头孢美唑（CMZ）和庆大霉素（GM）的抗菌活性进行了测试。测试菌株数量在1980年为587株，1981年为700株。金黄色葡萄球菌对ABPC和CEZ耐药菌株的频率（最低抑菌浓度：大于或等于25微克/毫升）在年度变化中明显增加。1981年以10(8)CFU/毫升接种量测试的CEZ耐药菌株百分比为12.3%，但CMZ的同一百分比仅为0.6%。
