An-Foraker S H, Fong-Mui K K
Acta Cytol. 1982 Nov-Dec;26(6):814-8.
Our experience of six and one-half years with cyto-diagnosis of pancreatic and related lesions is presented. We studied 22 cases of direct (perioperative and endoscopic) aspiration (group A) and 14 cases of percutaneous aspiration using ultrasound guidance (group B). Cytohistologic correlation in the direct aspiration cases and cytoclinical correlation in the percutaneous aspiration cases showed a specificity of 90% in group A and 100% in group B. Sensitivity was 100% in group A and 72.7% in group B. Predictive value of positive results was 92% in group A and 100% in group B. Eight of ten positive cancer cases in group A were confirmed by initial endoscopic tissue biopsies. One periampullary duodenal aspiration and one bile aspirate were cytologically positive, with negative endoscopic biopsy; final clinical evaluation with laparotomy confirmed these two cases as cancer. Thus, cytodiagnosis was more sensitive than tissue biopsy.
本文介绍了我们在胰腺及相关病变细胞诊断方面六年半的经验。我们研究了22例直接（围手术期和内镜下）穿刺抽吸病例（A组）和14例超声引导下经皮穿刺抽吸病例（B组）。直接穿刺抽吸病例的细胞组织学相关性以及经皮穿刺抽吸病例的细胞临床相关性显示，A组特异性为90%，B组为100%。A组敏感性为100%，B组为72.7%。A组阳性结果的预测值为92%，B组为100%。A组10例阳性癌症病例中有8例通过最初的内镜组织活检得到证实。1例壶腹周围十二指肠抽吸和1例胆汁抽吸细胞学检查呈阳性，但内镜活检为阴性；最终通过剖腹手术的临床评估证实这两例为癌症。因此，细胞诊断比组织活检更敏感。
