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Defective neutrophil chemotaxis corrected by levamisole in Crohn's disease.

作者信息

Patrone F, Dallegri F, Sacchetti C

出版信息

Acta Hepatogastroenterol (Stuttg). 1978 Aug;25(4):322-3.

PMID:696210
Abstract

In a 26-year-old man with Crohn's disease, evaluation of the neutrophil polymorphonuclear (PMN) function showed marked impairment of chemotaxis, while NBT tests, phagocytosis, random migration and adhesiveness were all normal. PMN chemotaxis was found normal after levamisole therapy.

摘要

相似文献

1
Defective neutrophil chemotaxis corrected by levamisole in Crohn's disease.
Acta Hepatogastroenterol (Stuttg). 1978 Aug;25(4):322-3.
2
Neutrophil function in surgical patients: in vitro correlation of abnormal neutrophil chemotaxis by Levamisole.外科患者的中性粒细胞功能：左旋咪唑导致中性粒细胞趋化异常的体外相关性
Surgery. 1979 May;85(5):543-8.
3
Effect of long-term therapy with sulphasalazine, levamisole, corticosteroids and ascorbic acid and of disease activity on polymorphonuclear leukocyte function in patients with ulcerative colitis.柳氮磺胺吡啶、左旋咪唑、皮质类固醇和抗坏血酸长期治疗及疾病活动对溃疡性结肠炎患者多形核白细胞功能的影响。
Hepatogastroenterology. 1985 Apr;32(2):81-6.
4
Severe acute polyarthropathy associated with levamisole therapy in a patient with Crohn's disease.
Eur J Rheumatol Inflamm. 1984;7(2):63-5.
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[Letter: Crohn's disease and levamisole].
Nouv Presse Med. 1974 Oct 19;3(35):2265.
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Defective neutrophil motility and recurrent infection. In vitro and in vivo effects of levamisole.中性粒细胞运动缺陷与反复感染。左旋咪唑的体内外效应。
Clin Exp Immunol. 1978 Jul;33(1):142-9.
7
Circulating growth-regulator oncogene alpha contributes to neutrophil priming and interleukin-8-directed mucosal recruitment into chronic lesions of patients with Crohn's disease.循环生长调节致癌基因α促进中性粒细胞启动以及白细胞介素-8介导的黏膜募集至克罗恩病患者的慢性病变部位。
Eur Cytokine Netw. 1998 Dec;9(4):647-53.
8
Levamisole in Crohn's disease: a randomized, double-blind, placebo-controlled clinical trial.
Am J Gastroenterol. 1987 Jun;82(6):536-9.
9
In vitro stimulation of neutrophil motility by levamisole: maintenance of cgmp levels in chemotactically stimulated levamisole-treated neutrophils.左旋咪唑对中性粒细胞运动的体外刺激：经左旋咪唑处理的趋化刺激中性粒细胞中 cGMP 水平的维持。
J Immunol. 1976 Aug;117(2):428-32.
10
[Crohn's disease of the colon treated with high doses of levamisole].
Nouv Presse Med. 1978 Dec 2;7(43):3942.

引用本文的文献

1
In vivo assessment of granulocyte migration to diseased bowel in Crohn's disease.克罗恩病中粒细胞向病变肠段迁移的体内评估
Gut. 1985 Apr;26(4):378-83. doi: 10.1136/gut.26.4.378.