Fink A I, Jordan A J, Bunke A, Fong D
Trans Ophthalmol Soc U K (1962). 1982 Apr;102 (Pt 1):125-8.
Thirty-four eyes (25 patients) with diagnosed chronic open angle glaucoma on maximal medical therapy were studied to determine whether argon laser trabecular surgery was a desirable alternative to carbonic anhydrase therapy. Ninety-four per cent of patients responded favourably to argon laser trabecular surgery as an alternative to carbonic anhydrase therapy. The average pressure drop was 9.9 mm Hg. Interestingly, there was a mean drop of 4.2 mm Hg in the contralateral eye. There was minimal, if any, iris response although there was a small but probably not clinically significant decrease in corneal endothelial cell count. Blanching of the trabecular wall was used as the endpoint to help minimize post-laser pressure rise. Blacks and aphakic patients responded satisfactorily. Laser surgery is best reserved for those patients with a pretreatment intraocular pressure no higher than the 30 to 35 mm Hg level. Trabeculectomy, in spite of its known complications, offers a better prognosis in those cases where the pretreatment pressure exceeds the 30 to 35 mm Hg level.
对34只眼睛（25例患者）进行了研究，这些患者被诊断为慢性开角型青光眼且正在接受最大剂量的药物治疗，目的是确定氩激光小梁成形术是否是碳酸酐酶疗法的理想替代方案。94%的患者对氩激光小梁成形术作为碳酸酐酶疗法的替代方案反应良好。平均眼压下降了9.9毫米汞柱。有趣的是，对侧眼平均下降了4.2毫米汞柱。尽管角膜内皮细胞计数有轻微下降，但可能无临床意义，虹膜反应极小。小梁壁变白被用作终点指标，以帮助尽量减少激光后眼压升高。黑人和无晶状体患者反应良好。激光手术最好保留给那些治疗前眼压不高于30至35毫米汞柱水平的患者。小梁切除术尽管有已知的并发症，但在那些治疗前眼压超过30至35毫米汞柱水平的病例中预后较好。
