Olsen F
Acta Pathol Microbiol Scand A. 1978 Mar;86(2):199-200. doi: 10.1111/j.1699-0463.1978.tb02032.x.
Experimentally-induced acute angiotensin hypertension has been shown to increase the permeability of cardial arteries and arterioles to plasma components within a few hours. Only in one of the coronary arteries was an increased and focal permeability for plasma components demonstrated, the penetration taking place into the entire thickness of the vessel wall. However, the permeability observed in intramyocardial small arteries and arterioles showed a distinct deposition of plasma components, both in the tunica intima and the tunica media and usually in the entire circumference of the vessels. The results support the view that an increased arterial permeability of the myocardial vessels for plasma components is an important initial stage in the development of hypertensive vascular disease of the heart.
实验性诱导的急性血管紧张素性高血压已被证明在数小时内会增加心肌动脉和小动脉对血浆成分的通透性。仅在一条冠状动脉中观察到血浆成分的通透性增加且呈局灶性，渗透发生在血管壁的全层。然而，在心肌内小动脉和微动脉中观察到的通透性表现为血浆成分在血管内膜和中膜均有明显沉积，且通常累及血管的整个圆周。这些结果支持这样一种观点，即心肌血管对血浆成分的动脉通透性增加是心脏高血压性血管疾病发展的一个重要初始阶段。
