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[高脂血症患者的黄瘤病]

[Xanthomatosis in patients with hyperlipoproteinemia].

作者信息

Kusić M, Stanković K, Gavrilović M

出版信息

Zb Vojnomed Akad. 1982;24:14-8.

PMID:6964904
Abstract

The clinical findings in 63 patients with xanthomas were analysed. Among them 5 had xanthelasmas and normal lipids. The largest group (37) consisted of females with xanthelasmas and heterozygotic form of hyperlipoproteinemia (HLP) type II. In this group HDL cholesterol values (1,5 mmol/l) were normal and ischemic heart disease (IHD) was rare. However, in 14 males HDL values (1,1 mml/l) were low while IHD was common. Cholesterol deposits in the folds of the palm (xanthochtomia striata palmaris), tuberous xanthoma and peripheral artery changes were characteristical findings for all three patients with HLP type III. In patients with HLP type IV and eruptive xanthomas, obesity was common finding (4/4) and disturbed glycoregulation (2/4) and triglyceride values were very high (X = 61,1 mmol/l).

摘要

对63例患有黄瘤的患者的临床发现进行了分析。其中5例患有睑黄瘤且血脂正常。最大的一组(37例)为患有睑黄瘤和杂合子型II型高脂蛋白血症(HLP)的女性。该组高密度脂蛋白胆固醇值(1.5 mmol/l)正常,缺血性心脏病(IHD)罕见。然而,14例男性的高密度脂蛋白值(1.1 mmol/l)较低,而IHD很常见。手掌褶皱处的胆固醇沉积(掌纹黄瘤)、结节性黄瘤和外周动脉改变是所有3例III型HLP患者的特征性表现。在IV型HLP和发疹性黄瘤患者中,肥胖是常见表现(4/4),糖调节紊乱(2/4),甘油三酯值非常高(X = 61.1 mmol/l)。

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