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注射的14C - 己烯雌酚在鸡和产蛋母鸡体内的分布。全身放射自显影和脉冲计数。

Distribution of injected 14C-diethylstilbestrol in the chicken and laying hen. Whole body autoradiography and impulse counting.

作者信息

Bengtsson S G

出版信息

Acta Vet Scand. 1978;19(2):254-62. doi: 10.1186/BF03547630.

DOI:10.1186/BF03547630
PMID:696537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8366370/
Abstract

Distribution of intramuscularly administered C-diethylstilbestrol(DES)in the chicken and laying hen was studied by whole body autoradiography and impulse counting techniques. In both groups the liver showed the highest concentration of C. The C-level of the chicken liver and bile appeared greater than the same level in the hen. The C-content of the hen kidney was twice that found in the chicken. These findings could mean that the metabolic and excretory function of the kidney is less developed in the young chicken than in the adult bird and that the chicken liver may compensate for insufficient kidney function. The lower G-concentration of the chicken adrenal as compared to the hen, could indicate a reduced physiological activity of the young adrenal. The accumulation of radioactivity in the membrane of the follicular yolk should represent excretion. Low C-content was found in the skeletal muscle. It is concluded that consumer products based mainly on the liver from DES-treated chickens should not be used for consumption.

摘要

通过全身放射自显影和脉冲计数技术研究了肌肉注射己烯雌酚(DES)在鸡和产蛋母鸡体内的分布。在两组中,肝脏显示出最高的C浓度。鸡肝脏和胆汁中的C水平似乎高于母鸡中的相同水平。母鸡肾脏的C含量是鸡的两倍。这些发现可能意味着幼鸡肾脏的代谢和排泄功能不如成年鸡发达,并且鸡肝脏可能补偿肾脏功能的不足。与母鸡相比,鸡肾上腺的G浓度较低,这可能表明幼肾上腺的生理活性降低。放射性物质在卵泡卵黄膜中的积累应代表排泄。在骨骼肌中发现C含量较低。得出的结论是,主要基于用DES处理过的鸡的肝脏的消费品不应供人食用。

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Distribution of injected 14C-diethylstilbestrol in the chicken and laying hen. Whole body autoradiography and impulse counting.注射的14C - 己烯雌酚在鸡和产蛋母鸡体内的分布。全身放射自显影和脉冲计数。
Acta Vet Scand. 1978;19(2):254-62. doi: 10.1186/BF03547630.
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本文引用的文献

1
Autoradiographic studies on the distribution of labelled drugs in the body.关于标记药物在体内分布的放射自显影研究。
Prog Nucl Energy 6 Biol Sci. 1959;2:29-35.
2
Metabolism of C14-diethylstilbestrol in the chicken: retention and excretion.鸡体内C14 - 己烯雌酚的代谢:潴留与排泄
Endocrinology. 1962 Jun;70:880-5. doi: 10.1210/endo-70-6-880.
3
Metabolism of C14-diethylstilbestrol in the chicken: conversion in vivo.鸡体内C14 - 己烯雌酚的代谢:体内转化
Endocrinology. 1962 Jun;70:886-9. doi: 10.1210/endo-70-6-886.
4
DISTRIBUTION OF INJECTED 14C-OESTRONE AND 14C-DIETHYLSTILBOESTROL. WHOLE ANIMAL AUTORADIOGRAPHY AND IMPULSE COUNTING.注射的14C-雌酮和14C-己烯雌酚的分布。全动物放射自显影和脉冲计数。
Acta Endocrinol (Copenh). 1963 Aug;43:587-91. doi: 10.1530/acta.0.0430587.
5
THE AUTORADIOGRAPHIC DISTRIBUTION PATTERN AFTER ADMINISTRATION OF DIETHYLSTILBOESTROL COMPARED WITH THAT OF NATURAL OESTROGENS.己烯雌酚给药后的放射自显影分布模式与天然雌激素的比较。
Acta Endocrinol (Copenh). 1963 Aug;43:561-70. doi: 10.1530/acta.0.0430561.
6
Autoradiographic distribution studies with natural oestrogens.天然雌激素的放射自显影分布研究。
Acta Endocrinol (Copenh). 1963 May;43:75-86. doi: 10.1530/acta.0.0430075.
7
Studies on the distribution and fate of S35-labelled benzylpenicillin in the body.关于S35标记的苄青霉素在体内的分布及转归的研究。
Acta Radiol Suppl. 1954;118:1-110.
8
The metabolic pattern of C14-diethylstilbestrol.C14 - 己烯雌酚的代谢模式
Endocrinology. 1953 Aug;53(2):163-70. doi: 10.1210/endo-53-2-163.
9
The antigen-binding capacity of the peptide chains of horse antibodies.马抗体肽链的抗原结合能力。
Biochem J. 1966 Jul;100(1):69-72. doi: 10.1042/bj1000069.
10
Effect of stilbestrol dipropionate on egg production and growth of reproductive organs in poultry.己烯雌酚二丙酸酯对家禽产蛋及生殖器官生长的影响。
Indian J Exp Biol. 1972 Jan;10(1):34-6.