Golding L R, Groves L K, Peter M, Jacobs G, Sukalac R, Nosé Y, Loop F D
Ann Thorac Surg. 1980 Jan;29(1):66-9. doi: 10.1016/s0003-4975(10)61630-x.
A new, simple left ventricular assist system has been developed and its use in experimental animals has been evaluated. The system achieves ventricular drainage by a transaortic valve cannula and utilizes a new centrifugal pump; the blood access is unique in requiring only a simple end-to-side synthetic graft anastomosis to the ascending aorta. Adequate pulsatility is obtained by concomitant use of an intraaortic balloon pump. This case report documents our initial clinical experience with this system in a postoperative patient with profound left ventricular failure unresponsive to all usual treatment. There was temporary recovery of left ventricular function upon decannulation after five and a half days of assist pumping. Despite the eventual death of the patient, the system functioned adequately, suggesting that it has good potential for use in a small, selected group of patients.
一种新型的、简单的左心室辅助系统已被研发出来,并已在实验动物身上评估了其应用效果。该系统通过经主动脉瓣插管实现心室引流,并采用了一种新型离心泵;血液接入方式独特,只需在升主动脉上进行简单的端侧人造血管吻合。通过同时使用主动脉内球囊泵可获得足够的搏动性。本病例报告记录了我们在一名术后出现严重左心室衰竭且对所有常规治疗均无反应的患者中使用该系统的初步临床经验。在辅助泵血五天半后拔管时,左心室功能出现了暂时恢复。尽管患者最终死亡,但该系统运行良好,表明它在一小部分经过挑选的患者中具有良好的应用潜力。