Alpha 1-antitrypsin phenotypes in Northern Sweden.

By means of isoelectric focusing the alpha 1-antitrypsin phenotypes were examined in 1,869 Swedes from northern Sweden, 300 Finns and 217 Swedish Lapps. The M2 frequency was low among the Lapps and in the northeastern part of Sweden. The frequencies of the S and Z genes were low in the Lapps and in the north-Swedish population. The frequencies of rare phenotypes among Finns from northern Finland were significantly higher than among Finns from southwestern Finland and Aland Islanders.