Love J W, Jahnke E J, McFadden R B, Murray J J, Latimer R G, Gebhart W F, Freidell H V, Fisher M B, Urquhart R R, Greditzer A
J Thorac Cardiovasc Surg. 1980 Apr;79(4):625-7.
Symptomatic coronary artery disease in patients with chronic renal failure can complicate their management in a dialysis program. Hypotension associated with hemodialysis and the anemia of chronic renal disease can produce anginal episodes refractory to medical management. Untreated coronary artery disease may be a contraindication to renal transplantation in an otherwise acceptable candidate. We have encountered three cases of coronary artery disease severe enough to necessitate coronary bypass in patients from our long-term hemodialysis program. All three patients had uncomplicated postoperative courses, none had perioperative infarction, and in all three patients postoperative angiography demonstrated patency of all grafts. One patient subsequently underwent successful renal transplantation; the other two patients have continued in hemodialyses since bypass. We believe our experience and the reported experience of others confirm the feasibility of coronary bypass grafting in patients with chronic renal failure.
慢性肾衰竭患者的症状性冠状动脉疾病会使其透析治疗过程变得复杂。与血液透析相关的低血压以及慢性肾病贫血可引发药物治疗难以控制的心绞痛发作。未经治疗的冠状动脉疾病可能会成为原本合适的肾移植候选人进行肾移植的禁忌证。我们在长期血液透析项目的患者中遇到了3例冠状动脉疾病严重到需要进行冠状动脉搭桥手术的病例。所有3例患者术后过程均无并发症,均未发生围手术期梗死,且所有3例患者术后血管造影均显示所有移植血管通畅。1例患者随后成功进行了肾移植;另外2例患者自搭桥手术后继续接受血液透析治疗。我们相信我们的经验以及其他人报告的经验证实了慢性肾衰竭患者进行冠状动脉搭桥术的可行性。