Fouts A C, Kraus S J
J Infect Dis. 1980 Feb;141(2):137-143. doi: 10.1093/infdis/141.2.137.
Vaginal discharge is the most common complaint and Trichomonas vaginalis vaginitis the most frequently diagnosed problem among women attending the DeKalb County Georgia, Veneral Disease Clinic. Despite this prevalence, the 1837 observations of Donné are the criteria frequently used in the clinical and laboratory diagnosis of trichomoniasis. Our study shows that a purulent, frothy discharge is indeed a characteristic of trichomonal vaginitis, but if it is used as the sole diagnostic criterion, 88% of women with trichomonal vaginitis will not be identified and 29% will be erroneously diagnosed as infected. Donné's wet-mount test remains highly specific, but culture will detect twice as many trichomonas infections. There is a positive association between trichomoniasis and gonococcal cervicitis, failure to use contraceptive techniques, and lack of yeast in the wet mount of vaginal secretions.
阴道分泌物异常是佐治亚州迪卡尔布县性病诊所就诊女性中最常见的主诉，滴虫性阴道炎是最常被诊断出的问题。尽管发病率如此之高，但唐内1837年的观察结果仍是滴虫病临床和实验室诊断中常用的标准。我们的研究表明，脓性、泡沫状分泌物确实是滴虫性阴道炎的一个特征，但如果将其作为唯一的诊断标准，88%的滴虫性阴道炎女性患者将无法被确诊，29%的患者会被误诊为感染。唐内的湿片检查仍然具有高度特异性，但培养法检测到的滴虫感染数量是其两倍。滴虫病与淋菌性宫颈炎、未采用避孕技术以及阴道分泌物湿片中缺乏酵母菌之间存在正相关。
