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Virus-immune cytotoxic T-cell activity following negative selection of alloreactive precursor lymphocytes.

作者信息

Bennink J R, Doherty P C

出版信息

Transplant Proc. 1980 Mar;12(1):172-4.

PMID:6966098
Abstract

Results obtained using negative selection protocols indicate that it is possible to obtain vaccinia-virus-specific killing of cells expressing H-2 types other than those encountered during physiologic development in thymus. This response has been found to be neither reciprocal for different H-2 types, nor identical for influenza and vaccinia viruses. Prior priming with virus apparently suppresses the capacity of T cells to be sensitized to H-2-different virus-infected cells.

摘要

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