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[胸腺素对人淋巴细胞亚群的体外作用]

[Effect of thymosin on human lymphocyte subpopulations in vitro].

作者信息

Shergin S M, Shubinskiĭ G Z, Kozhevnikov V S, Musatov M I, Kudaeva O T

出版信息

Biull Eksp Biol Med. 1980 Feb;89(2):192-4.

PMID:6966166
Abstract

The incubation of healthy donors peripheral blood lymphocytes with thymosin was shown to increase the content of high avide "active" lymphocytes bearing receptors for SRBC, lymphocytes bearing receptors for C(2) component of complement and for Fc-portion of immunoglobulins. The proportion of cap-forming Ig-positive lymphocytes was shown to increase too. The role of T and B lymphocyte subpopulations and their precursors as thymosin action target cells is discussed.

摘要

健康供体的外周血淋巴细胞与胸腺素一起孵育后,发现带有绵羊红细胞(SRBC)受体的高亲和力“活性”淋巴细胞、带有补体C(2)成分受体和免疫球蛋白Fc段受体的淋巴细胞的含量增加。形成帽状的Ig阳性淋巴细胞的比例也显示增加。文中讨论了T和B淋巴细胞亚群及其前体作为胸腺素作用靶细胞的作用。

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