先天性无胸腺裸鼠（nu/nu）的腹腔中有携带Thy-1的免疫活性辅助性T细胞。
Congenitally athymic nude (nu/nu) mice have Thy-1-bearing immunocompetent helper T cells in their peritoneal cavity.
作者信息
Ishikawa H, Saito K
出版信息
J Exp Med. 1980 Apr 1;151(4):965-8. doi: 10.1084/jem.151.4.965.
Abstract
Heavily irradiated peritoneal cells (PC) from congenitally athymic nude (nu/nu) mice markedly restored the impaired in vitro antibody response of nu/nu spleen cells to sheep erythrocyte antigens (T-dependent antigen), whereas irradiated spleen or lymph node cells from nu/nu mice had no effect on the response. This activity of the irradiated PC of nu/nu mice was completely abolished by treatment with anti-Thy-1.2 antiserum plus normal guinea pig serum (C') and is, therefore, attributable to a function of matured T cells.
摘要
来自先天性无胸腺裸鼠（nu/nu）的受到大量照射的腹膜细胞（PC）显著恢复了nu/nu脾细胞对绵羊红细胞抗原（T 依赖性抗原）受损的体外抗体反应，而来自 nu/nu 小鼠的经照射的脾细胞或淋巴结细胞对该反应没有影响。用抗 Thy-1.2 抗血清加正常豚鼠血清（补体）处理后，nu/nu 小鼠经照射的 PC 的这种活性完全被消除，因此，这可归因于成熟 T 细胞的功能。
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Humoral and cell mediated responses in vitro of spleen cells from mice with thymic aplasia (nude mice).胸腺发育不全小鼠（裸鼠）脾细胞的体外体液免疫和细胞介导免疫反应
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