Roelants G E, Loor F, von Boehmer H, Sprent J, Hägg L B, Mayor K S, Rydén A
Eur J Immunol. 1975 Feb;5(2):127-31. doi: 10.1002/eji.1830050211.
The simultaneous detection of Ig and theta on the surface of mouse lymphocytes permits the detection of four cell types (Ig-theta-, Ig-theta+, Ig+theta-, and Ig+theta+) which also have distinct electrophoretic profiles. All types are present in variable proportions in all lymphoid organs studied. Results obtained in congenitally athymic nude mice and in T-deprived mice define a new type of lymphocyte, the Ig-theta+weak. This cell is non-recirculating, Ig-, with a low density of theta and a slow electrophoretic mobility. It is a candidate for a T-committed prethymic cell.
同时检测小鼠淋巴细胞表面的Ig和θ，可识别出四种细胞类型（Ig-θ-、Ig-θ+、Ig+θ-和Ig+θ+），它们也具有不同的电泳图谱。在所有研究的淋巴器官中，所有类型细胞的比例各不相同。在先天性无胸腺裸鼠和T细胞缺失小鼠中获得的结果定义了一种新型淋巴细胞，即Ig-θ+弱阳性细胞。这种细胞不参与再循环，无Ig，θ密度低，电泳迁移缓慢。它是胸腺前T定向细胞的一个候选细胞。
