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肺动脉起源异常左冠状动脉的铊-201心肌显像。内科及外科治疗前后的应用。

Thallium-201 myocardial imaging in anomalous left coronary artery arising from the pulmonary artery. Applications before and after medical and surgical treatment.

作者信息

Finley J P, Howman-Giles R, Gilday D L, Olley P M, Rowe R D

出版信息

Am J Cardiol. 1978 Oct;42(4):675-80. doi: 10.1016/0002-9149(78)90640-9.

DOI:10.1016/0002-9149(78)90640-9
PMID:696649
Abstract

Thallium-201 myocardial imaging was performed on six patients with an anomalous left coronary artery arising from the pulmonary artery. Initial images in three children (aged 4 months, 12 months and 2 1/2 years, respectively) demonstrated anterolateral perfusion defects in agreement with the electrocardiographic localization of infarction. Repeat imaging in two patients 2 to 3 months later, after clinical improvement with anticongestive therapy, demonstrated a reduction in the perfusion defect. In 3 other patients (aged 16, 16 and 20 years, respectively) thallium-201 scans performed during exercise stress demonstrated normal myocardial perfusion 7 to 15 years after operation (ligation of anomalous left coronary in two, ligation plus bypass graft in one). Thallium-201 imaging appears to be helpful in monitoring changes in myocardial perfusion before and after medical or surgical treatment of an anomalous left coronary artery, and may shed light on the pathophysiology of the defect. A possible practical limitation of thallium-201 imaging in this condition is the difficulty of imaging subendocardial infarction.

摘要

对6例左冠状动脉起源于肺动脉的患者进行了铊-201心肌显像。3例儿童患者(分别为4个月、12个月和2岁半)的初始图像显示前外侧灌注缺损,与心电图梗死定位相符。2例患者在接受抗充血治疗临床症状改善后2至3个月进行重复显像,显示灌注缺损有所减轻。另外3例患者(分别为16岁、16岁和20岁)在运动负荷试验中进行的铊-201扫描显示,术后7至15年心肌灌注正常(2例为结扎异常左冠状动脉,1例为结扎加旁路移植)。铊-201显像似乎有助于监测左冠状动脉异常的药物或手术治疗前后心肌灌注的变化,并可能有助于了解缺损的病理生理学。在这种情况下,铊-201显像的一个可能实际限制是难以对心内膜下梗死进行显像。

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Thallium-201 myocardial imaging in anomalous left coronary artery arising from the pulmonary artery. Applications before and after medical and surgical treatment.肺动脉起源异常左冠状动脉的铊-201心肌显像。内科及外科治疗前后的应用。
Am J Cardiol. 1978 Oct;42(4):675-80. doi: 10.1016/0002-9149(78)90640-9.
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