Baranova F S, Berman A A, Zaretskaia Iu M
Biull Eksp Biol Med. 1980;89(1):35-6.
alpha 1-Antitrypsin (alpha 1-AT) decreases the intensity of human peripheral blood lymphocyte transformation stimulated by phytohemagglutinin. The degree of inhibition is influenced by the antiprotease activity of alpha 1-AT. It is shown that maximal inhibition of transplantation is 50%. Participation of alpha 1-AT in the control of biological activity of lymphoid tissue cells is suggested.
α1 -抗胰蛋白酶(α1 - AT)可降低植物血凝素刺激的人外周血淋巴细胞转化强度。抑制程度受α1 - AT的抗蛋白酶活性影响。结果表明,最大抑制率为50%。提示α1 - AT参与淋巴组织细胞生物活性的调控。