α1-抗胰蛋白酶对人淋巴细胞DNA生物合成的抑制作用
[Inhibition of DNA biosynthesis in human lymphocytes by alpha 1-antitrypsin].
作者信息
Bata J, Deviller P, Colobert L
出版信息
C R Acad Hebd Seances Acad Sci D. 1977 Dec 19;285(16):1499-501.
PMID:417823
Abstract
Incorporation of tritiated thymidine into human lymphocytes from tonsils is markedly inhibited by purified alpha1-antitrypsin-preparations. This inhibitory effect is observed in lymphocytes stimulated by a mitogen factor (phytohemagglutinin) as in non stimulated lymphocytes.
摘要
纯化的α1-抗胰蛋白酶制剂可显著抑制氚标记胸腺嘧啶核苷掺入扁桃体来源的人淋巴细胞。在有丝分裂原因子（植物血凝素）刺激的淋巴细胞以及未受刺激的淋巴细胞中均观察到这种抑制作用。
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