Frydén A, Kam-Hansen S, Maller R, Link H
Acta Neurol Scand. 1980 May;61(5):306-12. doi: 10.1111/j.1600-0404.1980.tb01497.x.
Patients with aseptic meningitis (AM) were examined with the active T cell rosette test, which has been claimed to reflect cell-mediated immunocompetence more accurately than determination of total T cells. Higher percentages of active T cells were demonstrated in CSF compared to blood regardless if specimens were obtained on days 1-4, days 5-10, or later than 20 days after onset of symptoms, Active T cell percentages in CSF decreased when values for specimens obtained on days 5-10 were compared with those taken later than 20 days after onset, while no significant variations of active T cell percentages in blood were observed. The percentages of total T cells were higher in CSF than blood in specimens from days 5-10, and later than 20 days after onset, but no significant fluctuations of total T cells occurred in either CSF or blood over the course of AM.
采用活性T细胞玫瑰花结试验对无菌性脑膜炎（AM）患者进行检查，据称该试验比总T细胞测定更能准确反映细胞介导的免疫能力。无论标本是在症状出现后的第1 - 4天、第5 - 10天还是症状出现20天后采集，脑脊液（CSF）中活性T细胞的百分比均高于血液。当将第5 - 10天采集的标本值与症状出现20天后采集的标本值进行比较时，脑脊液中活性T细胞百分比下降，而血液中活性T细胞百分比未观察到显著变化。在症状出现第5 - 10天以及症状出现20天后采集的标本中，脑脊液中总T细胞的百分比高于血液，但在无菌性脑膜炎病程中，脑脊液和血液中的总T细胞均未出现显著波动。
