Naess A
Scand J Infect Dis. 1982;14(1):5-9. doi: 10.3109/inf.1982.14.issue-1.02.
Lymphocyte subpopulations were determined in cerebrospinal fluid (CSF) from 11 patients with acute aseptic meningitis. The patients had a significantly higher percentage of T lymphocytes (as determined by rosette assays for sheep erythrocyte (E) receptor-bearing cells) in their CSF (86%) than in blood (62%). The percentage of complement (C) receptor-bearing cells was also higher in the CSF (47%), and the sum of E and C receptor positive cells was 133%, indicating a considerable number of cells carrying both receptors in the CSF in contrast to in peripheral blood. However, 8 patients with various neurological diseases had a mean of 65% C receptor-bearing cells in their CSF, while 17 others had 78 +/- 9% E receptor positive cells. Meningitis patients had a lower percentage of CSF Fc receptor-bearing cells (EA-RFC) than other patients. These results indicate the presence of a large percentage of CSF lymphocytes with both E and C receptors also in patients without meningeal disease, and suggest the recruitment of such cells into the CSF.
对11例急性无菌性脑膜炎患者的脑脊液（CSF）中的淋巴细胞亚群进行了测定。患者脑脊液中T淋巴细胞的百分比（通过对携带绵羊红细胞（E）受体的细胞进行玫瑰花结试验测定）显著高于血液中的百分比（分别为86%和62%）。脑脊液中携带补体（C）受体的细胞百分比也更高（47%），并且E和C受体阳性细胞的总和为133%，这表明与外周血相比，脑脊液中有相当数量的细胞同时携带这两种受体。然而，8例患有各种神经系统疾病的患者脑脊液中携带C受体的细胞平均百分比为65%，而另外17例患者携带E受体的阳性细胞百分比为78±9%。脑膜炎患者脑脊液中携带Fc受体的细胞（EA-RFC）百分比低于其他患者。这些结果表明，在没有脑膜疾病的患者中，脑脊液中也存在很大比例的同时携带E和C受体的淋巴细胞，并提示此类细胞被募集到脑脊液中。
