Bos J D, Hamerlinck F, Cormane R H
Br J Vener Dis. 1980 Apr;56(2):74-6. doi: 10.1136/sti.56.2.74.
In previous studies to assess the role of cell-mediated immunity in Treponema pallidum infection investigations of delayed type skin hypersensitivity tests, lymphocyte transformation test, leucocyte migration inhibition tests, and histological studies of the reticuloendothelial system have been performed. In this study, the numbers of T (thymus-dependent ) lymphoid cells in 10 patients with primary syphilis (eight untreated) were estimated by the rosette technique. Results indicate a significant decrease in the number of T lymphoid cells in patients with primary syphilis.
在以往评估细胞介导免疫在梅毒螺旋体感染中作用的研究中,已开展了迟发型皮肤超敏反应试验、淋巴细胞转化试验、白细胞游走抑制试验以及网状内皮系统的组织学研究。在本研究中,采用玫瑰花结技术对10例一期梅毒患者(8例未经治疗)的T(胸腺依赖性)淋巴细胞数量进行了估算。结果表明,一期梅毒患者的T淋巴细胞数量显著减少。