二硝基氯苯接触敏感豚鼠淋巴细胞的体外DNA合成
In vitro DNA synthesis in lymphocytes from DNCB contact-sensitive guinea pigs.
作者信息
Polak L
出版信息
Exp Cell Biol. 1980;48(5):356-66. doi: 10.1159/000163000.
PMID:6967023
Abstract
In vitro stimulation of lymphocytes from DNCB contact-sensitive guinea pigs is achieved by several DNP conjugates. Optimal results are obtained by DNP-modified macrophages. The degree of in vitro lymphocyte activity, demonstrated by DNA synthesis, depends on the cell origin, the interval between sensitization and harvest of lymphocytes and the immunological status of the animals.
摘要
几种二硝基苯（DNP）偶联物可实现对二硝基氯苯（DNCB）接触敏感豚鼠淋巴细胞的体外刺激。通过DNP修饰的巨噬细胞可获得最佳结果。通过DNA合成证明的体外淋巴细胞活性程度取决于细胞来源、致敏与淋巴细胞收获之间的间隔以及动物的免疫状态。
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