Goycoolea M V, Paparella M M, Juhn S K, Carpenter A M
Laryngoscope. 1980 Aug;90(8 Pt 1):1387-91.
A longitudinal sequential study of oval and round window changes in otitis media in an experimental animal (cat) using Eustachian tube obstruction was done. Thirty-two animals were used. In this first sequential study of the oval and round windows in otitis media, the continuum of round window membrane changes from 1 day to 6 months after obstruction revealed changes to be gradual and similar to those of the mucoperiostium. These changes are suitable for changes in permeability and suggest that this membrane is a very likely pathway from the middle to the inner ear. Bony fistulas were not observed and the oval window remained essentially unchanged in time, thus they were not considered routes into the inner ear. Other possible routes are discussed.
利用咽鼓管阻塞对实验动物（猫）中耳炎时椭圆窗和圆窗变化进行了纵向序列研究。共使用了32只动物。在这项关于中耳炎时椭圆窗和圆窗的首次序列研究中，阻塞后1天至6个月圆窗膜变化的连续过程显示变化是渐进的，且与黏膜骨膜的变化相似。这些变化适合通透性的改变，提示该膜很可能是从中耳到内耳的一条途径。未观察到骨瘘，椭圆窗在时间上基本保持不变，因此它们不被认为是进入内耳的途径。还讨论了其他可能的途径。
