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Selective killing of normal or neoplastic B cells by antibodies coupled to the A chain of ricin.
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5419-23. doi: 10.1073/pnas.77.9.5419.
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Immunotherapy of a murine B cell tumor with antibodies and F(ab')2 fragments against idiotypic determinants of its cell surface IgM.
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Anti-Thy 1.2 monoclonal antibody linked to ricin is a potent cell-type-specific toxin.
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5483-6. doi: 10.1073/pnas.77.9.5483.
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Xid and normal mice express a light chain-associated cross-reactive idiotype in response to (T,G)-A--L and (T,G)-A--L-mBSA.
J Immunol. 1986 May 15;136(10):3734-43.
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Whole ricin and recombinant ricin A chain idiotype-specific immunotoxins for therapy of the guinea pig L2C B cell leukemia.
J Immunol. 1987 Jun 15;138(12):4502-8.
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Growth inhibition of a B cell leukemia: evidence implicating an anti-idiotype immune response for protective tumor immunity.
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Anti-idiotypic mechanisms involved in suppression of a mouse B cell lymphoma, BCL1.
J Immunol. 1987 Jan 15;138(2):628-34.
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Idiotypic IgM on a B-cell surface requires processing for recognition by anti-idiotypic T cells.
Cell Immunol. 1993 Apr 1;147(2):411-24. doi: 10.1006/cimm.1993.1080.
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Directing ricin-based immunotoxins with targeting affibodies and KDEL signal peptide to cancer cells effectively induces apoptosis and tumor suppression.
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solid tumor targeting with recombinant VEGF-diphtheria immunotoxin.
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Clinical targeting recombinant immunotoxins for cancer therapy.
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Increased toxicity of diphtheria toxin for human lymphoblastoid cells following covalent linkage to anti-(human lymphocyte) globulin or its F(ab')2 fragment.
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The effect of anti-immunoglobulin antibodies on the in vitro proliferation and differentiation of normal and neoplastic murineB cells.
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A hybrid protein containing the toxic subunit of ricin and the cell-specific subunit of human chorionic gonadotropin. II. Biologic properties.
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Protein thiolation and reversible protein-protein conjugation. N-Succinimidyl 3-(2-pyridyldithio)propionate, a new heterobifunctional reagent.
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