Romanov V A
Zh Mikrobiol Epidemiol Immunobiol. 1980 Jul(7):82-5.
Immunization with absorbed DPT vaccine in 1 or 3 subcutaneous injections, as well as the intradermal or intracardiac immunization of guinea pigs with smallpox vaccine resulted in the accumulation of 0-positive lymphoyctes, determined by the cytotoxic test, in the lymph nodes. On the 7th day after the intracardiac injection of smallpox vaccine in massive doses a sharp decrease in the content of 0-positive lymphocytes was observed. The number of small lymphocytes with surface immunoglobulin receptors detected by immunofluorescence remains unchanged in the animals of all groups at any period of the experiment.
用吸附百日咳、白喉、破伤风疫苗进行1次或3次皮下注射免疫，以及用天花疫苗对豚鼠进行皮内或心内免疫后，通过细胞毒性试验测定，可在淋巴结中发现0阳性淋巴细胞的聚集。在心内大量注射天花疫苗后第7天，观察到0阳性淋巴细胞含量急剧下降。在实验的任何时期，通过免疫荧光检测到的具有表面免疫球蛋白受体的小淋巴细胞数量在所有组的动物中均保持不变。
