Akaza H, Kobayashi K, Umeda T, Niijima T
J Urol. 1980 Dec;124(6):827-8. doi: 10.1016/s0022-5347(17)55686-4.
Infiltrating lymphocytes were separated from human seminoma tissue obtained surgically. The relative distributions of B and T lymphocytes, and a subset of T lymphocytes with IgG-Fc receptors were measured by the rosette-forming method in peripheral blood and in seminoma tissue from 7 patients with pure seminoma of the testis. The proportions of T and TG cells were increased in seminoma tissue compared to those of peripheral blood from the same patients, whereas the proportion of B cells did not change. This result might correlate with the favorable prognosis of seminoma usually accompanied with lymphocytic infiltration.
从手术获取的人精原细胞瘤组织中分离出浸润淋巴细胞。采用玫瑰花结形成法，检测了7例睾丸纯精原细胞瘤患者外周血和精原细胞瘤组织中B淋巴细胞、T淋巴细胞以及具有IgG-Fc受体的T淋巴细胞亚群的相对分布。与同一患者的外周血相比，精原细胞瘤组织中T细胞和TG细胞的比例增加，而B细胞比例未变。这一结果可能与精原细胞瘤通常伴有淋巴细胞浸润的良好预后相关。
