Waller B F, Roberts W C
Am J Cardiol. 1980 Dec 1;46(6):956-62. doi: 10.1016/0002-9149(80)90351-3.
In 32 necropsy patients who died within 30 days of an aortocoronary bypass operation performed for relief of angina pectoris, the lumens in 42 (95 percent) of 44 nonbypassed and in 52 (100 percent) or 52 bypassed arteries were narrowed 76 to 100 percent in cross-sectional area by atherosclerotic plaque. Of 616 five mm segments of the 44 nonbypassed arteries examined histologically, 292 (47 percent) were narrowed 76 to 100 percent in cross-sectional area by atherosclerotic plaque; of 728 segments examined in the 52 bypassed arteries, 375 (52 percent) were similarly narrowed. Thirty-two (73 percent) of the 44 nonbypassed coronary arteries (in 23 patients) had been judged to be narrowed 50 percent or less in diameter on preoperative coronary angiography, but at necropsy 31 (97 percent) of these arteries were narrowed 76 to 100 percent in cross-sectional area and the other artery was narrowed 51 to 75 percent. Thus, significant amounts of atherosclerotic plaque tend to be present at necropsy in all three major coronary systems of patients with angina pectoris who die early after an aortocoronary bypass operation.
在32例因缓解心绞痛而接受主动脉冠状动脉搭桥手术并在术后30天内死亡的尸检患者中，44条未搭桥动脉中的42条（95%）以及52条搭桥动脉中的52条（100%）的管腔，其横截面积因动脉粥样硬化斑块而狭窄了76%至100%。在对44条未搭桥动脉进行组织学检查的616个5毫米节段中，292个（47%）节段的横截面积因动脉粥样硬化斑块而狭窄了76%至100%；在52条搭桥动脉中检查的728个节段中，375个（52%）节段也有类似程度的狭窄。44条未搭桥冠状动脉中的32条（73%，涉及23例患者）在术前冠状动脉造影中被判定直径狭窄50%或更小，但尸检时这些动脉中有31条（97%）的横截面积狭窄了76%至100%，另一条动脉狭窄了51%至75%。因此，在因心绞痛接受主动脉冠状动脉搭桥手术后早期死亡的患者的所有三个主要冠状动脉系统中，尸检时往往存在大量动脉粥样硬化斑块。
