Petty H R, Ware B R, Liebes L F, Pelle E, Silber R
Blood. 1981 Feb;57(2):250-5.
The electrophoretic mobility distributions of hairy cells, normal monocytes. CLL, and normal lymphocytes isolated from blood were determined by electrophoretic light scattering. Values obtained for hairy cells, 1.52 X 10(-4) cm2/V . sec, were indistinguishable from that of normal monocytes. The mobility of CLL lymphocytes was similar to that of normal B cells. After exposure to neuraminidase, hairy cells revealed a homogeneous distribution with a reduced mobility of 0.55 X 10(-4) cm2/V . sec, while normal monocytes showed a heterogeneous distribution of electrophoretic mobilities suggestive of subpopulations. The electrokinetic behavior of hairy cells thus differs from that or normal and CLL lymphocytes before, and from that of monocytes after, treatment with neuraminidase. The hairy cell therefore possesses a distinct pattern of surface charge properties that clearly distinguish it from the circulating B cells, T cells, or monocytes.
通过电泳光散射测定从血液中分离出的毛细胞、正常单核细胞、慢性淋巴细胞和正常淋巴细胞的电泳迁移率分布。毛细胞的迁移率值为1.52×10⁻⁴ cm²/V·秒，与正常单核细胞的值无明显差异。慢性淋巴细胞的迁移率与正常B细胞相似。用神经氨酸酶处理后，毛细胞呈现均匀分布，迁移率降低至0.55×10⁻⁴ cm²/V·秒，而正常单核细胞则显示出提示亚群的电泳迁移率异质性分布。因此，毛细胞的电动行为在处理前与正常和慢性淋巴细胞不同，在处理后与单核细胞不同。毛细胞因此具有独特的表面电荷特性模式，使其与循环中的B细胞、T细胞或单核细胞明显区分开来。
