Smith B A, Ware B R, Weiner R S
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2388-91. doi: 10.1073/pnas.73.7.2388.
The electrophoretic mobilities of mononuclear white cells from the peripheral blood of normal subjects and leukemic patients were measured. Analysis of both fresh and cryopreserved samples of each type showed that cryopreservation had no distinguishable effect on the electrophoretic distribution of either normal or leukemic cells. Mode mobilities (mobilities at which maximum intensities are observed) of cells from nine leukemic patients were 7-28% below the average mode mobility of normal cells. The standard deviation of the electrophoretic mobilities of normal cells was 2%. Normal cells had an asymmetric, often bimodal, electrophoretic distribution; leukemic cells consistently had a single symmetric distribution.
测量了正常受试者和白血病患者外周血中单核白细胞的电泳迁移率。对每种类型的新鲜样本和冷冻保存样本进行分析表明，冷冻保存对正常细胞或白血病细胞的电泳分布没有明显影响。9名白血病患者细胞的迁移率峰值（观察到最大强度时的迁移率）比正常细胞的平均迁移率峰值低7%-28%。正常细胞电泳迁移率的标准差为2%。正常细胞具有不对称的、通常为双峰的电泳分布；白血病细胞始终具有单一的对称分布。
