Celada A, Barras C, Benzonana G, Jeannet M
Tissue Antigens. 1980 Mar;15(3):283-8. doi: 10.1111/j.1399-0039.1980.tb00919.x.
The distribution of HLA antigens was studied in 40 patients suffering from systemic lupus erythematosus. For loci A and B, increased frequencies of A1, B8 and the presence of only one B antigen were found. Nevertheless, in relation to the number of antigens tested, this increase was not significant. For the DRw locus, DRw3 was significantly increased (P < 0.001, after correction for the 39 antigens tested). However, the patients with DRw3 did not show any correlation with a specific clinical picture or the presence in their serum of lymphocytotoxic antibodies or autoantibodies against T and B lymphocytes.
对40例系统性红斑狼疮患者的HLA抗原分布进行了研究。对于A和B位点，发现A1、B8频率增加且仅存在一种B抗原。然而，就所检测抗原的数量而言，这种增加并不显著。对于DRw位点，DRw3显著增加（在对所检测的39种抗原进行校正后，P<0.001）。然而，携带DRw3的患者与特定临床表现或其血清中针对T和B淋巴细胞的淋巴细胞毒性抗体或自身抗体的存在并无相关性。
