Barber K A, Jackson R
Can Med Assoc J. 1983 Jul 15;129(2):139-41.
In two of five infants with neonatal lupus erythematosus the signs of the disease did not appear until the children had been exposed to direct sunlight. This suggests that an environmental factor may be required for the development of the disease in some patients. Three of the five patients, together with their mothers, had the HLA (histocompatibility) antigens A1 and B8, which supports the concept that individuals may be genetically susceptible to lupus erythematosus.
在五名新生儿红斑狼疮患儿中,有两名直到暴露于直射阳光下才出现该病症状。这表明在某些患者中,疾病的发展可能需要环境因素。五名患者中的三名及其母亲具有HLA(组织相容性)抗原A1和B8,这支持了个体可能在遗传上易患红斑狼疮的观点。