[含4-氨基苯基链烷酸基团且具有潜在抗炎活性的杂环化合物。II. 2-取代吗啉衍生物]
[Heterocyclic compounds containing a 4-aminophenylalkanoic acid group with potential antiinflammatory activity. II. 2-Substituted morpholine derivatives].
作者信息
Picciòla G, Ravenna F, Carenini G, Manzardo S, Gentili P
出版信息
Farmaco Sci. 1981 Jan;36(1):47-60.
PMID:6970682
Abstract
Derivatives of 4-aminophenylalkanoic acids where the amino groups is part of a 3-morpholinone or a 2-morpholine ring, substituted in position 2 with a methyl, phenyl, 2-thienyl or (2-cyclohexyl)phenoxymethyl residue are described. Pharmacological evaluation aimed at evidencing analgesic and anti-inflammatory activity gave no noteworthy results.
摘要
描述了4-氨基苯基链烷酸的衍生物，其中氨基是3-吗啉酮或2-吗啉环的一部分，在2位被甲基、苯基、2-噻吩基或(2-环己基)苯氧基甲基残基取代。旨在证明镇痛和抗炎活性的药理学评价未得出显著结果。
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