Palva T, Reitamo S, Konttinen Y T, Häyry P, Rinne J
Int J Pediatr Otorhinolaryngol. 1981 Jan;3(1):71-8. doi: 10.1016/0165-5876(81)90021-5.
Middle ear mucosal biopsies were taken from 11 patients with middle ear effusion. In 8 cases the specimens were sufficiently large to allow detailed studies of the submucosal cellular components. It appears that in noncomplicated serous middle ear effusion, due to mechanical obstruction of the Eustachian tube, the submucosa is not infiltrated by inflammatory cells. In all types of mucoid effusion of variable duration, various lymphocyte classes, i.e. T- and B-lymphocytes and plasma cells, were present, suggesting a normal cellular immune response. The lack of granulocytes seems to indicate that there is no submucosal infection.
从11例中耳积液患者中获取中耳黏膜活检样本。8例患者的样本足够大，能够对黏膜下细胞成分进行详细研究。似乎在非复杂性浆液性中耳积液中，由于咽鼓管机械性阻塞，黏膜下层未被炎性细胞浸润。在所有不同病程的黏液样积液类型中，均存在各种淋巴细胞类别，即T淋巴细胞、B淋巴细胞和浆细胞，提示细胞免疫反应正常。缺乏粒细胞似乎表明不存在黏膜下感染。
