Richter E
Ann Otol Rhinol Laryngol. 1981 Mar-Apr;90(2 Pt 1):121-5. doi: 10.1177/000348948109000205.
The density of vestibular hair cells and the number of neurons in Scarpa's ganglion were estimated for 11 temporal bones with endolymphatic hydrops. The ten subjects from which these bones were taken all exhibited decreased caloric response (when tested), fluctuating hearing loss, and episodic vertigo. The degeneration of vestibular sense organs was found within the "normal" range for all except one case, which showed total degeneration of the posterior crista ampullaris. Ganglion cell counts in all cases were low. In three of the ten subjects, counts fell below the lowest values seen in a sample of "normal" ears. These three subjects exhibited fluctuating hearing loss and episodic vertigo for more than six years prior to death. In cases of unilateral endolymphatic hydrops there was no significant difference between counts in the affected and unaffected ear. Thus, the apparent ganglion cell degeneration may be due to ear disease other than endolymphatic hydrops.
对11例患有内淋巴积水的颞骨进行了前庭毛细胞密度和斯卡帕神经节中神经元数量的评估。取自这11例颞骨的10名受试者在接受测试时均表现出冷热试验反应降低、波动性听力损失和发作性眩晕。除1例后半规管壶腹嵴完全退化外，其余所有病例的前庭感觉器官退化均在“正常”范围内。所有病例的神经节细胞计数均较低。在这10名受试者中有3名，其计数低于“正常”耳样本中所见的最低值。这3名受试者在死亡前六年多一直表现出波动性听力损失和发作性眩晕。在单侧内淋巴积水的病例中，患耳和未患耳的计数之间没有显著差异。因此，明显的神经节细胞退化可能是由除内淋巴积水以外的耳部疾病引起的。
