Harrington T M, Davis D E
Chest. 1981 Jun;79(6):696-7. doi: 10.1378/chest.79.6.696.
Pleural pericarditis, fever, and a positive reaction for antinuclear antibody developed in a 50-year-old white woman while she was receiving methyldopa (500 mg daily). After withdrawal of the drug, there was complete resolution of the clinical signs and symptoms, as well as normalization of the patient's antinuclear antibody titer. To our knowledge, this is the first reported case of a clinical lupus-like syndrome induced by therapy with methyldopa.
一名50岁白人女性在服用甲基多巴（每日500毫克）时出现了胸膜心包炎、发热和抗核抗体阳性反应。停药后，临床体征和症状完全消退，患者的抗核抗体滴度也恢复正常。据我们所知，这是首例报道的由甲基多巴治疗引起的临床狼疮样综合征病例。
