与鼠白血病病毒感染细胞相关的总细胞表面抗原的鉴定。
Identification of the Gross cell surface antigen associated with murine leukemia virus-infected cells.
作者信息
Ledbetter J, Nowinski R C
出版信息
J Virol. 1977 Aug;23(2):315-22. doi: 10.1128/JVI.23.2.315-322.1977.
Abstract
The Gross cell surface antigen (GCSA) is produced by cells that are either exogenously infected with murine leukemia virus (MuLV) or are expressing endogenous MuLV genomes. In immune precipitation assays, GCSA was resolved into two serologically distinct 85,000- and 95,000-dalton viral proteins. These antigenic components are glycosylated forms of the polyprotein precursors of the MuLV internal structural proteins.
摘要
总细胞表面抗原（GCSA）由外源性感染鼠白血病病毒（MuLV）的细胞或表达内源性MuLV基因组的细胞产生。在免疫沉淀试验中，GCSA被分解为两种血清学上不同的85000道尔顿和95000道尔顿的病毒蛋白。这些抗原成分是MuLV内部结构蛋白多蛋白前体的糖基化形式。
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